811 research outputs found
Fatigue failure of regenerator screens in a high frequency Stirling engine
Failure of Stirling Space Power Demonstrator Engine (SPDE) regenerator screens was investigated. After several hours of operation the SPDE was shut down for inspection and on removing the regenerator screens, debris of unknown origin was discovered along with considerable cracking of the screens in localized areas. Metallurgical analysis of the debris determined it to be cracked-off-deformed pieces of the 41 micron thickness Type 304 stainless steel wire screen. Scanning electron microscopy of the cracked screens revealed failures occurring at wire crossovers and fatigue striations on the fracture surface of the wires. Thus, the screen failure can be characterized as a fatigue failure of the wires. The crossovers were determined to contain a 30 percent reduction in wire thickness and a highly worked microstructure occurring from the manufacturing process of the wire screens. Later it was found that reduction in wire thickness occurred because the screen fabricator had subjected it to a light cold-roll process after weaving. Installation of this screen left a clearance in the regenerator allowing the screens to move. The combined effects of the reduction in wire thickness, stress concentration (caused by screen movement), and highly worked microstructure at the wire crossovers led to the fatigue failure of the screens
Radio Galaxy Zoo: Knowledge Transfer Using Rotationally Invariant Self-Organising Maps
With the advent of large scale surveys the manual analysis and classification
of individual radio source morphologies is rendered impossible as existing
approaches do not scale. The analysis of complex morphological features in the
spatial domain is a particularly important task. Here we discuss the challenges
of transferring crowdsourced labels obtained from the Radio Galaxy Zoo project
and introduce a proper transfer mechanism via quantile random forest
regression. By using parallelized rotation and flipping invariant Kohonen-maps,
image cubes of Radio Galaxy Zoo selected galaxies formed from the FIRST radio
continuum and WISE infrared all sky surveys are first projected down to a
two-dimensional embedding in an unsupervised way. This embedding can be seen as
a discretised space of shapes with the coordinates reflecting morphological
features as expressed by the automatically derived prototypes. We find that
these prototypes have reconstructed physically meaningful processes across two
channel images at radio and infrared wavelengths in an unsupervised manner. In
the second step, images are compared with those prototypes to create a
heat-map, which is the morphological fingerprint of each object and the basis
for transferring the user generated labels. These heat-maps have reduced the
feature space by a factor of 248 and are able to be used as the basis for
subsequent ML methods. Using an ensemble of decision trees we achieve upwards
of 85.7% and 80.7% accuracy when predicting the number of components and peaks
in an image, respectively, using these heat-maps. We also question the
currently used discrete classification schema and introduce a continuous scale
that better reflects the uncertainty in transition between two classes, caused
by sensitivity and resolution limits
Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro
1. The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from anin vitro slice preparation.
2. Stimulation with suprathreshold intensities evoked l-IPSPs with typical durations of 600–900 msec at resting membrane potential. Conductance increases of 15–60% were measured at the peak amplitude of l-IPSPs (150–250 msec poststimulus).
3. The duration of the conductance increases during l-IPSPs displayed a significant voltage dependence, decreasing as the membrance potential was depolarized and increasing with hyperpolarization.
4. The reversal potential of l-IPSPs is significantly altered by reductions in the extracellular potassium concentration. Therefore it is concluded that l-IPSPs in rat neocortical neurons are generated by the activation of a potassium conductance.
5. l-IPSPs exhibit stimulation fatigue. Stimulation with a frequency of 1 Hz produces a complete fatigue of the conductance increases during l-IPSPs after approximately 20 consecutive stimuli. Recovery from this fatigue requires minutes.
6. l-IPSPs are not blocked by bicuculline but are blocked by baclofen
Electron Magnetic Resonance: The Modified Bloch Equation
We find a modified Bloch equation for the electronic magnetic moment when the
magnetic moment explicitly contains a diamagnetic contribution (a magnetic
field induced magnetic moment arising from the electronic orbital angular
momentum) in addition to the intrinsic magnetic moment of the electron. The
modified Bloch is coupled to equations of motion for the position and momentum
operators. In the presence of static and time varying magnetic field
components, the magnetic moment oscillates out of phase with the magnetic field
and power is absorbed by virtue of the magnetic field induced magnetic moment,
even in the absence of coupling to the environment. We explicitly work out the
spectrum and absorption for the case of a state electron
Radio Galaxy Zoo: Machine learning for radio source host galaxy cross-identification
We consider the problem of determining the host galaxies of radio sources by
cross-identification. This has traditionally been done manually, which will be
intractable for wide-area radio surveys like the Evolutionary Map of the
Universe (EMU). Automated cross-identification will be critical for these
future surveys, and machine learning may provide the tools to develop such
methods. We apply a standard approach from computer vision to
cross-identification, introducing one possible way of automating this problem,
and explore the pros and cons of this approach. We apply our method to the 1.4
GHz Australian Telescope Large Area Survey (ATLAS) observations of the Chandra
Deep Field South (CDFS) and the ESO Large Area ISO Survey South 1 (ELAIS-S1)
fields by cross-identifying them with the Spitzer Wide-area Infrared
Extragalactic (SWIRE) survey. We train our method with two sets of data: expert
cross-identifications of CDFS from the initial ATLAS data release and
crowdsourced cross-identifications of CDFS from Radio Galaxy Zoo. We found that
a simple strategy of cross-identifying a radio component with the nearest
galaxy performs comparably to our more complex methods, though our estimated
best-case performance is near 100 per cent. ATLAS contains 87 complex radio
sources that have been cross-identified by experts, so there are not enough
complex examples to learn how to cross-identify them accurately. Much larger
datasets are therefore required for training methods like ours. We also show
that training our method on Radio Galaxy Zoo cross-identifications gives
comparable results to training on expert cross-identifications, demonstrating
the value of crowdsourced training data
Long-Term Potentiation: One Kind or Many?
Do neurobiologists aim to discover natural kinds? I address this question in this chapter via a critical analysis of classification practices operative across the 43-year history of research on long-term potentiation (LTP). I argue that this 43-year history supports the idea that the structure of scientific practice surrounding LTP research has remained an obstacle to the discovery of natural kinds
Predictors of CNS Injury as Measured by Proton Magnetic Resonance Spectroscopy in the Setting of Chronic HIV infection and CART
The reasons for persistent brain dysfunction in chronically HIV-infected persons on stable combined antiretroviral therapies (CART) remain unclear. Host and viral factors along with their interactions were examined in 260 HIV-infected subjects who underwent magnetic resonance spectroscopy (MRS) Metabolite concentrations (NAA/Cr, Cho/Cr, MI/Cr and Glx/Cr) were measured in the basal ganglia, the frontal white matter and grey matter and the best predictive models were selected using a bootstrap-enhanced Akaike Information Criterion (AIC). Depending on the metabolite and brain region, age, race, HIV RNA concentration, ADC stage, duration of HIV infection, nadir CD4, and/or their interactions were predictive of metabolite concentrations, particularly the basal ganglia NAA/Cr and the mid-frontal NAA/Cr and Glx/Cr whereas current CD4 and the CPE index rarely or did not predict these changes. These results show for the first time that host and viral factors related to both current and past HIV status contribute to persisting cerebral metabolite abnormalities and provide a framework for further understanding neurological injury in the setting of chronic and stable disease
The perseverance of Pacioli's goods inventory accounting system
This paper details sources of the 'undoubtedly strange' (Yamey, 1994a, p.119) system of goods inventory records described in Pacioli’s 1494 bookkeeping treatise and traces the longevity and widespread use of this early perpetual inventory recording (EPIR) system in English language texts. By doing so and contrasting this system with the bookkeeping treatment of modern texts, it is shown that the EPIR system persisted as the dominant form of goods inventory accounting for between 400 and 500 years and that the reasons for its demise are worthy of further consideration and research
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